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» Genomic Database Applications in DISCO
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BMCBI
2010
219views more  BMCBI 2010»
13 years 2 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
VLDB
2007
ACM
128views Database» more  VLDB 2007»
14 years 7 months ago
Periscope/SQ: Interactive Exploration of Biological Sequence Databases
Life science laboratories today have to rely on procedural techniques to store and manage large sequence datasets. Procedural techniques are cumbersome to use and are often very i...
Sandeep Tata, Willis Lang, Jignesh M. Patel
BMCBI
2008
104views more  BMCBI 2008»
13 years 7 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
USENIX
1994
13 years 8 months ago
Splicing UNIX into a Genome Mapping Laboratory
The Whitehead Institute/MIT Center for Genome Research is responsible for a number of large genome mapping efforts, the scale of which create problems of data and workflow managem...
Lincoln Stein, Andre Marquis, Robert Dredge, Mary ...
BMCBI
2004
96views more  BMCBI 2004»
13 years 7 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...