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BMCBI
2005
198views more  BMCBI 2005»
13 years 10 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
RECOMB
2008
Springer
14 years 11 months ago
Ab Initio Whole Genome Shotgun Assembly with Mated Short Reads
Next Generation Sequencing (NGS) technologies are capable of reading millions of short DNA sequences both quickly and cheaply. While these technologies are already being used for r...
Paul Medvedev, Michael Brudno
IPPS
2002
IEEE
14 years 3 months ago
Parallel Out-of-Core Algorithm for Genome-Scale Enumeration of Metabolic Systemic Pathways
Systemic pathways-oriented approaches to analysis of metabolic networks are effective for small networks but are computationally infeasible for genome scale networks. Current comp...
Nagiza F. Samatova, Al Geist, George Ostrouchov, A...
NCA
2007
IEEE
13 years 10 months ago
A data reduction approach for resolving the imbalanced data issue in functional genomics
Learning from imbalanced data occurs frequently in many machine learning applications. One positive example to thousands of negative instances is common in scientific applications...
Kihoon Yoon, Stephen Kwek
BMCBI
2005
127views more  BMCBI 2005»
13 years 10 months ago
Genomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns"
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
Etienne Larsabal, Antoine Danchin