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BMCBI
2004
146views more  BMCBI 2004»
13 years 8 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
IPPS
2007
IEEE
14 years 3 months ago
SWARM: A Parallel Programming Framework for Multicore Processors
Due to fundamental physical limitations and power constraints, we are witnessing a radical change in commodity microprocessor architectures to multicore designs. Continued perform...
David A. Bader, Varun Kanade, Kamesh Madduri
KDD
2008
ACM
243views Data Mining» more  KDD 2008»
14 years 9 months ago
Permu-pattern: discovery of mutable permutation patterns with proximity constraint
Pattern discovery in sequences is an important problem in many applications, especially in computational biology and text mining. However, due to the noisy nature of data, the tra...
Meng Hu, Jiong Yang, Wei Su
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
14 years 2 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
BMCBI
2005
137views more  BMCBI 2005»
13 years 8 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...