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EOR
2006
89views more  EOR 2006»
13 years 7 months ago
Clique-detection models in computational biochemistry and genomics
Many important problems arising in computational biochemistry and genomics have been formulated in terms of underlying combinatorial optimization models. In particular, a number h...
Sergiy Butenko, Wilbert E. Wilhelm
NAR
2007
90views more  NAR 2007»
13 years 7 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...
RECOMB
2005
Springer
14 years 7 months ago
Reversals of Fortune
Abstract. The objective function of the genome rearrangement problems allows the integration of other genome-level problems so that they may be solved simultaneously. Three example...
David Sankoff, Chunfang Zheng, Aleksander Lenert
BIBE
2004
IEEE
179views Bioinformatics» more  BIBE 2004»
13 years 11 months ago
Incorporating Ontology-Driven Similarity Knowledge into Functional Genomics: An Exploratory Study
This research explores the feasibility of semantic similarity approaches to supporting predictive tasks in functional genomics. It aims to establish potential relationships betwee...
Francisco Azuaje, Olivier Bodenreider
BMCBI
2005
246views more  BMCBI 2005»
13 years 7 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...