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ISMB
2007
13 years 9 months ago
Connecting quantitative regulatory-network models to the genome
Yue Pan, Tim Durfee, Joseph Bockhorst, Mark Craven
BMCBI
2008
80views more  BMCBI 2008»
13 years 7 months ago
Computational evaluation of TIS annotation for prokaryotic genomes
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
Gang-Qing Hu, Xiaobin Zheng, Li-Ning Ju, Huaiqiu Z...
BMCBI
2010
91views more  BMCBI 2010»
13 years 7 months ago
Coverage statistics for sequence census methods
We study the shape of coverage functions resulting from the sequencing of random genome fragments, and show that they can be described by Galton-Watson trees. This extends standar...
Steven N. Evans, Valerie Hower, Lior Pachter
BMCBI
2010
132views more  BMCBI 2010»
13 years 7 months ago
Next generation tools for genomic data generation, distribution, and visualization
Background: With the rapidly falling cost and availability of high throughput sequencing and microarray technologies, the bottleneck for effectively using genomic analysis in the ...
David A. Nix, Tonya L. Di Sera, Brian K. Dalley, B...
BMCBI
2010
126views more  BMCBI 2010»
13 years 7 months ago
Cgaln: fast and space-efficient whole-genome alignment
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
Ryuichiro Nakato, Osamu Gotoh