Sciweavers

680 search results - page 67 / 136
» Genomic computing: explanatory modelling for functional geno...
Sort
View
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
ESCIENCE
2007
IEEE
14 years 19 days ago
Grid-Enabling an Efficient Algorithm for Demanding Global Optimization Problems in Genetic Analysis
Abstract. We study the implementation on grid systems of an efficient algorithm for demanding global optimization problems. Specifically, we consider problems arising in the geneti...
Mahen Jayawardena, Sverker Holmgren
BMCBI
2006
87views more  BMCBI 2006»
13 years 8 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2011
13 years 3 months ago
Multithreaded comparative RNA secondary structure prediction using stochastic context-free grammars
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
Zsuzsanna Sukosd, Bjarne Knudsen, Morten Vaerum, J...
BMCBI
2010
179views more  BMCBI 2010»
13 years 8 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...