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BMCBI
2010
134views more  BMCBI 2010»
13 years 8 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
WABI
2010
Springer
178views Bioinformatics» more  WABI 2010»
13 years 7 months ago
Haplotype Inference on Pedigrees with Recombinations and Mutations
Abstract. Haplotype Inference (HI) is a computational challenge of crucial importance in a range of genetic studies, such as functional genomics, pharmacogenetics and population ge...
Yuri Pirola, Paola Bonizzoni, Tao Jiang
JCB
2006
140views more  JCB 2006»
13 years 8 months ago
HAPLOFREQ-Estimating Haplotype Frequencies Efficiently
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
Eran Halperin, Elad Hazan
BMCBI
2006
161views more  BMCBI 2006»
13 years 8 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
RECOMB
2010
Springer
14 years 3 months ago
A Novel Abundance-Based Algorithm for Binning Metagenomic Sequences Using l-Tuples
Abstract. Metagenomics is the study of microbial communities sampled directly from their natural environment, without prior culturing. Among the computational tools recently develo...
Yu-Wei Wu, Yuzhen Ye