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BMCBI
2004
158views more  BMCBI 2004»
13 years 8 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2008
123views more  BMCBI 2008»
13 years 8 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
COMPUTER
2008
84views more  COMPUTER 2008»
13 years 8 months ago
e-Science, caGrid, and Translational Biomedical Research
We describe the informatics requirements of translational biomedical research projects and how e-Science tools can be used to address them. We use pattern templates to describe the...
Joel H. Saltz, Tahsin M. Kurç, Shannon Hast...
PRICAI
2004
Springer
14 years 2 months ago
Computational Methods for Identification of Human microRNA Precursors
MicroRNA (miRNA), one of non-coding RNAs (ncRNAs), regulates gene expression directly by arresting the messenger RNA (mRNA) translation, which is important for identifying putative...
Jin-Wu Nam, Wha-Jin Lee, Byoung-Tak Zhang
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
14 years 12 days ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald