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» Geometry of gene expression dynamics
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ISMB
2000
13 years 9 months ago
A Probabilistic Learning Approach to Whole-Genome Operon Prediction
We present a computational approach to predicting operons in the genomes of prokaryotic organisms. Our approach uses machine learning methods to induce predictive models for this ...
Mark Craven, David Page, Jude W. Shavlik, Joseph B...
BIBE
2007
IEEE
108views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
On the Design of Oligos for Gene Synthesis
— Methods for reliable synthesis of long genes offer great promise for protein synthesis via expression of synthetic genes, with applications to improved analysis of protein stru...
Chris Thachuk, Anne Condon
BMCBI
2010
85views more  BMCBI 2010»
13 years 7 months ago
Robust test method for time-course microarray experiments
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
Insuk Sohn, Kouros Owzar, Stephen L. George, Sujon...
BMCBI
2006
156views more  BMCBI 2006»
13 years 7 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
BMCBI
2010
124views more  BMCBI 2010»
13 years 7 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...