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» Geometry of gene expression dynamics
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BICOB
2009
Springer
13 years 5 months ago
A Biclustering Method to Discover Co-regulated Genes Using Diverse Gene Expression Datasets
We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
Doruk Bozdag, Jeffrey D. Parvin, Ümit V. &Cce...
BMCBI
2010
115views more  BMCBI 2010»
13 years 7 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2006
239views more  BMCBI 2006»
13 years 7 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
CEC
2003
IEEE
13 years 11 months ago
Dynamics of gene expression in an artificial genome
Abstract- Complex systems techniques provide a powerful tool to study the emergent properties of networks of interacting genes. In this study we extract models of genetic regulator...
Kai Willadsen, Janet Wiles
IDEAL
2004
Springer
14 years 26 days ago
Building Genetic Networks for Gene Expression Patterns
Building genetic regulatory networks from time series data of gene expression patterns is an important topic in bioinformatics. Probabilistic Boolean networks (PBNs) have been deve...
Wai-Ki Ching, Eric S. Fung, Michael K. Ng