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BMCBI
2008
141views more  BMCBI 2008»
13 years 7 months ago
MiRTif: a support vector machine-based microRNA target interaction filter
Background: MicroRNAs (miRNAs) are a set of small non-coding RNAs serving as important negative gene regulators. In animals, miRNAs turn down protein translation by binding to the...
Yuchen Yang, Yu-Ping Wang, Kuo-Bin Li
COMPLIFE
2006
Springer
13 years 11 months ago
Promoter Prediction Using Physico-Chemical Properties of DNA
The ability to locate promoters within a section of DNA is known to be a very difficult and very important task in DNA analysis. We document an approach that incorporates the conce...
Philip Uren, R. Mike Cameron-Jones, Arthur H. J. S...
JCC
2008
117views more  JCC 2008»
13 years 7 months ago
Prediction of protein structural class using novel evolutionary collocation-based sequence representation
: Knowledge of structural classes is useful in understanding of folding patterns in proteins. Although existing structural class prediction methods applied virtually all state-of-t...
Ke Chen 0003, Lukasz A. Kurgan, Jishou Ruan
SIGKDD
2008
150views more  SIGKDD 2008»
13 years 7 months ago
Learning to improve area-under-FROC for imbalanced medical data classification using an ensemble method
This paper presents our solution for KDD Cup 2008 competition that aims at optimizing the area under ROC for breast cancer detection. We exploited weighted-based classification me...
Hung-Yi Lo, Chun-Min Chang, Tsung-Hsien Chiang, Ch...
BMCBI
2004
93views more  BMCBI 2004»
13 years 7 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...