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JIB
2006
220views more  JIB 2006»
13 years 8 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
BMCBI
2008
105views more  BMCBI 2008»
13 years 9 months ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
FUIN
2011
358views Cryptology» more  FUIN 2011»
13 years 10 days ago
Unsupervised and Supervised Learning Approaches Together for Microarray Analysis
In this article, a novel concept is introduced by using both unsupervised and supervised learning. For unsupervised learning, the problem of fuzzy clustering in microarray data as ...
Indrajit Saha, Ujjwal Maulik, Sanghamitra Bandyopa...
KDD
2008
ACM
206views Data Mining» more  KDD 2008»
14 years 9 months ago
Identifying biologically relevant genes via multiple heterogeneous data sources
Selection of genes that are differentially expressed and critical to a particular biological process has been a major challenge in post-array analysis. Recent development in bioin...
Zheng Zhao, Jiangxin Wang, Huan Liu, Jieping Ye, Y...
BMCBI
2010
136views more  BMCBI 2010»
13 years 9 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...