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BMCBI
2010
183views more  BMCBI 2010»
13 years 10 months ago
Active learning for human protein-protein interaction prediction
Background: Biological processes in cells are carried out by means of protein-protein interactions. Determining whether a pair of proteins interacts by wet-lab experiments is reso...
Thahir P. Mohamed, Jaime G. Carbonell, Madhavi Gan...
BMCBI
2010
165views more  BMCBI 2010»
13 years 10 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
BMCBI
2006
118views more  BMCBI 2006»
13 years 10 months ago
Exploration of biological network centralities with CentiBiN
Background: The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Central...
Björn H. Junker, Dirk Koschützki, Falk S...
BMCBI
2006
161views more  BMCBI 2006»
13 years 10 months ago
A method for rapid similarity analysis of RNA secondary structures
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
Na Liu, Tianming Wang
TCS
2008
13 years 9 months ago
GemCell: A generic platform for modeling multi-cellular biological systems
The mass and complexity of biological information requires computer-aided simulation and analysis to help scientists achieve understanding and guide experimentation. Although livi...
Hila Amir-Kroll, Avital Sadot, Irun R. Cohen, Davi...