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BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...
BMCBI
2010
154views more  BMCBI 2010»
13 years 8 months ago
LINNAEUS: A species name identification system for biomedical literature
Background: The task of recognizing and identifying species names in biomedical literature has recently been regarded as critical for a number of applications in text and data min...
Martin Gerner, Goran Nenadic, Casey M. Bergman
BMCBI
2010
86views more  BMCBI 2010»
13 years 8 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2010
147views more  BMCBI 2010»
13 years 8 months ago
Indirect two-sided relative ranking: a robust similarity measure for gene expression data
Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
Louis Licamele, Lise Getoor
BMCBI
2010
90views more  BMCBI 2010»
13 years 8 months ago
Local alignment of generalized k-base encoded DNA sequence
Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
Nils Homer, Stanley F. Nelson, Barry Merriman
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