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» Hidden conformations in protein structures
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BIOSYSTEMS
2008
83views more  BIOSYSTEMS 2008»
13 years 7 months ago
Hydrophobic condensation and modular assembly model of protein folding
Despite several decades of intense study, protein folding problem remains elusive. In this paper, we review current knowledge and the prevailing thinking in the field, and summari...
Tian-Yow Tsong, Chin-Kun Hu, Ming-Chya Wu
NAR
2006
74views more  NAR 2006»
13 years 7 months ago
HHrep: de novo protein repeat detection and the origin of TIM barrels
HHrep is a web server for the de novo identification of repeats in protein sequences, which is based on the pairwise comparison of profile hidden Markov models (HMMs). Its main st...
Johannes Söding, Michael Remmert, Andreas Bie...
BMCBI
2010
148views more  BMCBI 2010»
13 years 7 months ago
Analysis of interactions between ribosomal proteins and RNA structural motifs
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
Giovanni Ciriello, Claudio Gallina, Concettina Gue...
CEC
2011
IEEE
12 years 7 months ago
Comparing alternative energy functions for the HP model of protein structure prediction
Abstract—Protein structure prediction is the problem of finding the functional conformation of a protein given only its amino uence. The HP lattice model is an abstract formulat...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
BMCBI
2010
153views more  BMCBI 2010»
13 years 7 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...