20 search results - page 3 / 4 » Hierarchical Classification of Gene Ontology Terms Using the... |
BMCBI
2008
13 years 11 months ago
2008
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
MCS
2010
Springer
14 years 3 months ago
2010
Springer
Abstract. The computational genome-wide annotation of gene functions requires the prediction of hierarchically structured functional classes and can be formalized as a multiclass, ...
TCBB
2010
13 years 9 months ago
2010
—The correct interpretation of many molecular biology experiments depends in an essential way on the accuracy and consistency of the existing annotation databases. Such databases...
BMCBI
2004
13 years 10 months ago
2004
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
CIKM
2005
Springer
14 years 4 months ago
2005
Springer
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...