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BMCBI
2008
102views more  BMCBI 2008»
13 years 9 months ago
Improving protein function prediction methods with integrated literature data
Background: Determining the function of uncharacterized proteins is a major challenge in the post-genomic era due to the problem's complexity and scale. Identifying a protein...
Aaron Gabow, Sonia M. Leach, William A. Baumgartne...
BMCBI
2006
239views more  BMCBI 2006»
13 years 9 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
161views more  BMCBI 2006»
13 years 9 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2005
106views more  BMCBI 2005»
13 years 9 months ago
Thesaurus-based disambiguation of gene symbols
Background: Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge. However, disambiguation of gene s...
Bob J. A. Schijvenaars, Barend Mons, Marc Weeber, ...
PRL
2007
180views more  PRL 2007»
13 years 8 months ago
Feature selection based on rough sets and particle swarm optimization
: We propose a new feature selection strategy based on rough sets and Particle Swarm Optimization (PSO). Rough sets has been used as a feature selection method with much success, b...
Xiangyang Wang, Jie Yang, Xiaolong Teng, Weijun Xi...