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BMCBI
2010
13 years 7 months ago
2010
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
BMCBI
2010
13 years 7 months ago
2010
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
BMCBI
2010
13 years 7 months ago
2010
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
BMCBI
2008
13 years 7 months ago
2008
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
BMCBI
2008
13 years 7 months ago
2008
Background: The local connectivity and global position of a protein in a protein interaction network are known to correlate with some of its functional properties, including its e...