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BMCBI
2006
174views more  BMCBI 2006»
13 years 8 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
BMCBI
2006
147views more  BMCBI 2006»
13 years 8 months ago
QPath: a method for querying pathways in a protein-protein interaction network
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
Tomer Shlomi, Daniel Segal, Eytan Ruppin, Roded Sh...
BMCBI
2006
133views more  BMCBI 2006»
13 years 8 months ago
An integrated approach to the prediction of domain-domain interactions
Background: The development of high-throughput technologies has produced several large scale protein interaction data sets for multiple species, and significant efforts have been ...
Hyunju Lee, Minghua Deng, Fengzhu Sun, Ting Chen
BMCBI
2006
141views more  BMCBI 2006»
13 years 8 months ago
Identification of consensus RNA secondary structures using suffix arrays
Background: The identification of a consensus RNA motif often consists in finding a conserved secondary structure with minimum free energy in an ensemble of aligned sequences. How...
Mohammad Anwar, Truong Nguyen, Marcel Turcotte
BMCBI
2008
111views more  BMCBI 2008»
13 years 8 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...