392 search results - page 45 / 79 » High-Precision Function Prediction using Conserved Interacti... |
BMCBI
2010
13 years 8 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
CBMS
2007
IEEE
14 years 3 months ago
2007
IEEE
This paper describes how high level biological knowledge obtained from ontologies such as the Gene Ontology (GO) can be integrated with low level information extracted from a Baye...
IJCAI
2007
13 years 10 months ago
2007
This paper describes how high level biological knowledge obtained from ontologies such as the Gene Ontology (GO) can be integrated with low level information extracted from a Baye...
BMCBI
2010
13 years 8 months ago
2010
Background: Small molecular cofactors or ligands play a crucial role in the proper functioning of cells. Accurate annotation of their target proteins and binding sites is required...
BMCBI
2004
13 years 8 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...