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ISBRA
2009
Springer
14 years 3 months ago
Using Gene Expression Modeling to Determine Biological Relevance of Putative Regulatory Networks
Identifying gene regulatory networks from high-throughput gene expression data is one of the most important goals of bioinformatics, but it remains difficult to define what makes a...
Peter Larsen, Yang Dai
BMCBI
2008
187views more  BMCBI 2008»
13 years 8 months ago
PSAT: A web tool to compare genomic neighborhoods of multiple prokaryotic genomes
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
BIODATAMINING
2008
96views more  BIODATAMINING 2008»
13 years 8 months ago
Fast approximate hierarchical clustering using similarity heuristics
Background: Agglomerative hierarchical clustering (AHC) is a common unsupervised data analysis technique used in several biological applications. Standard AHC methods require that...
Meelis Kull, Jaak Vilo
ICANNGA
2007
Springer
100views Algorithms» more  ICANNGA 2007»
14 years 17 days ago
Softening Splits in Decision Trees Using Simulated Annealing
Predictions computed by a classification tree are usually constant on axis-parallel hyperrectangles corresponding to the leaves and have strict jumps on their boundaries. The densi...
Jakub Dvorák, Petr Savický
ICDM
2009
IEEE
152views Data Mining» more  ICDM 2009»
14 years 3 months ago
SLIDER: Mining Correlated Motifs in Protein-Protein Interaction Networks
Correlated motif mining (CMM) is the problem to find overrepresented pairs of patterns, called motif pairs, in interacting protein sequences. Algorithmic solutions for CMM thereb...
Peter Boyen, Frank Neven, Dries Van Dyck, Aalt-Jan...