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BMCBI
2008
109views more  BMCBI 2008»
13 years 8 months ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
BMCBI
2010
160views more  BMCBI 2010»
13 years 8 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
BMCBI
2006
116views more  BMCBI 2006»
13 years 8 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
14 years 2 months ago
Improving Operon Prediction in E. coli
In bacterium, genes working in the same pathway or interacting with each other are often organized into operons. Currently, the prediction accuracy for operon/boundary gene pairs ...
PhuongAn Dam, Victor Olman, Ying Xu
BMCBI
2006
144views more  BMCBI 2006»
13 years 8 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...