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JCNS
2008
117views more  JCNS 2008»
13 years 8 months ago
Dendritic action potentials connect distributed dendrodendritic microcircuits
Lateral inhibition of cells surrounding an excited area is a key property of sensory systems, sharpening the preferential tuning of individual cells in the presence of closely rela...
Michele Migliore, Gordon M. Shepherd
ICGA
1997
122views Optimization» more  ICGA 1997»
13 years 10 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
BMCBI
2005
116views more  BMCBI 2005»
13 years 8 months ago
SuperLigands - a database of ligand structures derived from the Protein Data Bank
Background: Currently, the PDB contains approximately 29,000 protein structures comprising over 70,000 experimentally determined three-dimensional structures of over 5,000 differe...
Elke Michalsky, Mathias Dunkel, Andrean Goede, Rob...
NIPS
2004
13 years 10 months ago
Validity Estimates for Loopy Belief Propagation on Binary Real-world Networks
We introduce a computationally efficient method to estimate the validity of the BP method as a function of graph topology, the connectivity strength, frustration and network size....
Joris M. Mooij, Hilbert J. Kappen
BCB
2010
127views Bioinformatics» more  BCB 2010»
13 years 3 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...