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COMPSAC
2004
IEEE
13 years 11 months ago
Protein Functional Motion Query and Visualization
Function is a dynamic property closely related to the conformational mechanisms of the protein structure in its physiological environment. Efficient methods and tools for predicti...
Xiong Liu, Hassan A. Karimi, Lee-Wei Yang, Ivet Ba...
BMCBI
2010
176views more  BMCBI 2010»
13 years 8 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
14 years 1 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald
BMCBI
2004
208views more  BMCBI 2004»
13 years 7 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
NAR
2006
98views more  NAR 2006»
13 years 7 months ago
oGNM: online computation of structural dynamics using the Gaussian Network Model
An assessment of the equilibrium dynamics of biomolecular systems, and in particular their most cooperativefluctuationsaccessibleundernativestate conditions, is a first step towar...
Lee-Wei Yang, A. J. Rader, Xiong Liu, Christopher ...