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JCB
1998
92views more  JCB 1998»
13 years 7 months ago
Homology Detection via Family Pairwise Search
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
William Noble Grundy
BIBE
2005
IEEE
126views Bioinformatics» more  BIBE 2005»
14 years 1 months ago
Suboptimal Alignments Improve the Detection of Weak Homologs in Sequence Database Searches
PSI-BLAST remains one of the popular tools for searching remote homologs in sequence databases. We recently demonstrated that hybrid alignment can function as the alignment core f...
Yuheng Li, Mario Lauria, Ralf Bundschuh
ICPADS
2005
IEEE
14 years 1 months ago
Exploiting Multi-level Parallelism for Homology Search using General Purpose Processors
New biological experimental techniques are continuing to generate large amounts of data using DNA, RNA, human genome and protein sequences. The quantity and quality of data from t...
Xiandong Meng, Vipin Chaudhary
JCB
2007
106views more  JCB 2007»
13 years 7 months ago
Clustered Sequence Representation for Fast Homology Search
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
Michael Cameron, Yaniv Bernstein, Hugh E. Williams
CBMS
2007
IEEE
13 years 9 months ago
From Local Laboratory Data to Public Domain Database in Search of Indirect Association of Diseases: AJAX Based Gene Data Search
This paper presents an extensible schema for capturing laboratory gene variance data with its meta-data properties in a semi-structured environment. This paper also focuses on the...
Nawaz Khan, Ham Long, Shahedur Rahman, Tony Stockm...