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BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
CSB
2003
IEEE
106views Bioinformatics» more  CSB 2003»
14 years 24 days ago
Reconstruction of Ancestral Gene Order after Segmental Duplication and Gene Loss
As gene order evolves through a variety of chromosomal rearrangements, conserved segments provide important insight into evolutionary relationships and functional roles of genes. ...
Jun Huan, Jan Prins, Wei Wang 0010, Todd J. Vision
BMCBI
2006
249views more  BMCBI 2006»
13 years 7 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
NAR
1998
73views more  NAR 1998»
13 years 7 months ago
Identification and characterization of the RAD51 gene from the ciliate Tetrahymena thermophila
The RAD51 gene is a eukaryotic homolog of recA, a critical component in homologous recombination and DNA repair pathways in Escherichia coli. We have cloned the RAD51 homolog from...
Colin Campbell, Daniel P. Romero
BIOCOMP
2009
13 years 8 months ago
Improving Remote Homology Detection Using Sequence Properties and Position Specific Scoring Matrices
Current biological sequence comparison tools frequently fail to recognize matches between homologs when sequence similarity is below the twilight zone of less than 25% sequence id...
Gina Cooper, Michael L. Raymer