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JBI
2008
159views Bioinformatics» more  JBI 2008»
13 years 7 months ago
SEGS: Search for enriched gene sets in microarray data
Gene Ontology (GO) terms are often used to interpret the results of microarray experiments. The most common approach is to perform Fisher's exact tests to find gene sets anno...
Igor Trajkovski, Nada Lavrac, Jakub Tolar
NAR
2007
152views more  NAR 2007»
13 years 7 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....
JCB
2002
116views more  JCB 2002»
13 years 7 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
SSDBM
2003
IEEE
141views Database» more  SSDBM 2003»
14 years 23 days ago
The ed-tree: An Index for Large DNA Sequence Databases
The growing interest in genomic research has caused an explosive growth in the size of DNA databases making it increasely challenging to perform searches on them. In this paper, w...
Zhenqiang Tan, Xia Cao, Beng Chin Ooi, Anthony K. ...
BMCBI
2005
87views more  BMCBI 2005»
13 years 7 months ago
Efficient decoding algorithms for generalized hidden Markov model gene finders
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
William H. Majoros, Mihaela Pertea, Arthur L. Delc...