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CCS
2009
ACM
14 years 2 months ago
Privacy-preserving genomic computation through program specialization
In this paper, we present a new approach to performing important classes of genomic computations (e.g., search for homologous genes) that makes a significant step towards privacy...
Rui Wang, XiaoFeng Wang, Zhou Li, Haixu Tang, Mich...
BMCBI
2010
101views more  BMCBI 2010»
13 years 7 months ago
Hidden Markov model speed heuristic and iterative HMM search procedure
Background: Profile hidden Markov models (profile-HMMs) are sensitive tools for remote protein homology detection, but the main scoring algorithms, Viterbi or Forward, require con...
L. Steven Johnson, Sean R. Eddy, Elon Portugaly
GCB
1998
Springer
112views Biometrics» more  GCB 1998»
13 years 11 months ago
Combining diverse evidence for gene recognition in completely sequenced bacterial genomes
Analysis of a newly sequenced bacterial genome starts with identification of protein-coding genes. Functional assignment of proteins requires the exact knowledge of protein N-term...
Dmitrij Frishman, Andrey A. Mironov, Hans-Werner M...
BMCBI
2006
178views more  BMCBI 2006»
13 years 7 months ago
GOLEM: an interactive graph-based gene-ontology navigation and analysis tool
Background: The Gene Ontology has become an extremely useful tool for the analysis of genomic data and structuring of biological knowledge. Several excellent software tools for na...
Rachel S. G. Sealfon, Matthew A. Hibbs, Curtis Hut...
ACSC
2009
IEEE
14 years 2 months ago
Inference of Gene Expression Networks Using Memetic Gene Expression Programming
In this paper we aim to infer a model of genetic networks from time series data of gene expression profiles by using a new gene expression programming algorithm. Gene expression n...
Armita Zarnegar, Peter Vamplew, Andrew Stranieri