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ALMOB
2006
155views more  ALMOB 2006»
13 years 7 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2006
202views more  BMCBI 2006»
13 years 7 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
SIGIR
2008
ACM
13 years 7 months ago
Algorithmic mediation for collaborative exploratory search
We describe a new approach to information retrieval: algorithmic mediation for intentional, synchronous collaborative exploratory search. Using our system, two or more users with ...
Jeremy Pickens, Gene Golovchinsky, Chirag Shah, Pe...
SIGMOD
2004
ACM
88views Database» more  SIGMOD 2004»
14 years 7 months ago
Using Reasoning to Guide Annotation with Gene Ontology Terms in GOAT
High-quality annotation of biological data is central to bioinformatics. Annotation using terms from ontologies provides reliable computational access to data. The Gene Ontology (...
Michael Bada, Daniele Turi, Robin McEntire, Robert...
BIOINFORMATICS
2007
66views more  BIOINFORMATICS 2007»
13 years 7 months ago
Gene expression network analysis and applications to immunology
We address the problem of using expression data and prior biological knowledge to identify differentially expressed pathways or groups of genes. Following an idea of Ideker et al...
Serban Nacu, Rebecca Critchley-Thorne, Peter Lee, ...