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BMCBI
2010
87views more  BMCBI 2010»
15 years 2 months ago
Prodigal: prokaryotic gene recognition and translation initiation site identification
Background: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the num...
Doug Hyatt, Gwo-Liang Chen, Philip F. LoCascio, Mi...
BMCBI
2010
129views more  BMCBI 2010»
15 years 2 months ago
A temporal precedence based clustering method for gene expression microarray data
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in m...
Ritesh Krishna, Chang-Tsun Li, Vicky Buchanan-Woll...
BMCBI
2010
95views more  BMCBI 2010»
15 years 2 months ago
Spatio-structural granularity of biological material entities
Background: With the continuously increasing demands on knowledge- and data-management that databases have to meet, ontologies and the theories of granularity they use become more...
Lars Vogt
BMCBI
2010
129views more  BMCBI 2010»
15 years 2 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
BMCBI
2008
90views more  BMCBI 2008»
15 years 2 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...