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BMCBI
2010
136views more  BMCBI 2010»
13 years 10 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BMCBI
2008
163views more  BMCBI 2008»
13 years 10 months ago
Gene Ontology term overlap as a measure of gene functional similarity
Background: The availability of various high-throughput experimental and computational methods allows biologists to rapidly infer functional relationships between genes. It is oft...
Meeta Mistry, Paul Pavlidis
DC
2010
13 years 10 months ago
A knowledge-based analysis of global function computation
Consider a distributed system N in which each agent has an input value and each communication link has a weight. Given a global function, that is, a function f whose value depends...
Joseph Y. Halpern, Sabina Petride
BMCBI
2006
144views more  BMCBI 2006»
13 years 10 months ago
ProFAT: a web-based tool for the functional annotation of protein sequences
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
Charles Richard Bradshaw, Vineeth Surendranath, Bi...
BMCBI
2005
104views more  BMCBI 2005»
13 years 10 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...