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BMCBI
2010
13 years 7 months ago
2010
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
BMCBI
2010
13 years 7 months ago
2010
Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
BMCBI
2008
2008
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
13 years 7 months ago
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
BMCBI
2008
13 years 7 months ago
2008
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
BMCBI
2006
13 years 7 months ago
2006
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...