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140
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BMCBI
2004
158views more  BMCBI 2004»
15 years 2 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
140
Voted
BMCBI
2004
126views more  BMCBI 2004»
15 years 2 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
123
Voted
NAR
2002
67views more  NAR 2002»
15 years 2 months ago
The TRIPLES database: a community resource for yeast molecular biology
TRIPLES is a web-accessible database of TRansposonInsertion Phenotypes, Localization and Expression in Saccharomyces cerevisiae--a relational database housing nearly half a millio...
Anuj Kumar, Kei-Hoi Cheung, Nick P. Tosches, Peter...
103
Voted
NAR
2007
99views more  NAR 2007»
15 years 2 months ago
PATRIC: The VBI PathoSystems Resource Integration Center
The PathoSystems Resource Integration Center (PATRIC) is one of eight Bioinformatics Resource Centers (BRCs) funded by the National Institute of Allergy and Infection Diseases (NI...
E. E. Snyder, N. Kampanya, J. Lu, Eric K. Nordberg...
167
Voted
BMCBI
2008
166views more  BMCBI 2008»
15 years 1 months ago
QuantPrime - a flexible tool for reliable high-throughput primer design for quantitative PCR
Background: Medium- to large-scale expression profiling using quantitative polymerase chain reaction (qPCR) assays are becoming increasingly important in genomics research. A majo...
Samuel Arvidsson, Miroslaw Kwasniewski, Diego Maur...