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BMCBI
2006
156views more  BMCBI 2006»
13 years 7 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
TCBB
2010
91views more  TCBB 2010»
13 years 2 months ago
SCS: Signal, Context, and Structure Features for Genome-Wide Human Promoter Recognition
This paper integrates the signal, context and structure features for genome-wide promoter recognition, which is critical in many DNA sequence analysis tasks. First, CpG islands ar...
Jia Zeng, Xiaoyu Zhao, Xiao-Qin Cao, Hong Yan
EDBT
2010
ACM
117views Database» more  EDBT 2010»
14 years 2 months ago
Anchoring millions of distinct reads on the human genome within seconds
With the advent of next-generation DNA sequencing machines, there is an increasing need for the development of computational tools that can anchor accurately and expediently the m...
Tien Huynh, Michail Vlachos, Isidore Rigoutsos
IPPS
2003
IEEE
14 years 26 days ago
A Fast Algorithm for the Exhaustive Analysis of 12-Nucleotide-Long DNA Sequences. Applications to Human Genomics
We have developed a new algorithm that allows the exhaustive determination of words of up to 12 nucleotides in DNA sequences. It is fast enough as to be used at a genomic scale ru...
Vicente Arnau, Ignacio Marín
BIB
2010
103views more  BIB 2010»
13 years 5 months ago
Challenges of sequencing human genomes
Massively parallel sequencing technologies continue to alter the study of human genetics. As the cost of sequencing declines, next-generation sequencing (NGS) instruments and data...
Daniel C. Koboldt, Li Ding, Elaine R. Mardis, Rich...