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116
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BIBM
2008
IEEE
110views Bioinformatics» more  BIBM 2008»
15 years 9 months ago
Genome Alignments Using MPI-LAGAN
We develop a parallel algorithm for a widely used whole genome alignment method called LAGAN. We use the MPI-based protocol to develop parallel solutions for two phases of the alg...
Ruinan Zhang, Huzefa Rangwala, George Karypis
117
Voted
CIKM
2009
Springer
15 years 6 months ago
Suffix trees for very large genomic sequences
A suffix tree is a fundamental data structure for string searching algorithms. Unfortunately, when it comes to the use of suffix trees in real-life applications, the current metho...
Marina Barsky, Ulrike Stege, Alex Thomo, Chris Upt...
109
Voted
PSB
2004
15 years 4 months ago
An Evidence Ontology for Use in Pathway/Genome Databases
An important emerging need in Model Organism Databases (MODs) and other bioinformatics databases (DBs) is that of capturing the scientific evidence that supports the information wi...
Peter D. Karp, Suzanne M. Paley, Cynthia J. Kriege...
BMCBI
2006
124views more  BMCBI 2006»
15 years 2 months ago
Predicting transcription factor binding sites using local over-representation and comparative genomics
Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
Matthieu Defrance, Hélène Touzet
124
Voted
KES
2008
Springer
15 years 1 months ago
Classification of Sporadic and BRCA1 Ovarian Cancer Based on a Genome-Wide Study of Copy Number Variations
Abstract. Motivation: Although studies have shown that genetic alterations are causally involved in numerous human diseases, still not much is known about the molecular mechanisms ...
Anneleen Daemen, Olivier Gevaert, Karin Leunen, Va...