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» Humans in the Process: Architectural Implications
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CHI
2009
ACM
14 years 2 months ago
Adaptive information search: age-dependent interactions between cognitive profiles and strategies
Previous research has shown that older adults performed worse in web search tasks, and attributed poorer performance to a decline in their cognitive abilities. We conducted a stud...
Jessie Chin, Wai-Tat Fu, Thomas George Kannampalli...
DEBS
2007
ACM
14 years 2 months ago
High frequency distributed data stream event correlation to improve neonatal clinical management
Approximately eighteen percent (18%) of babies born in New South Wales (NSW), Australia require special care or neonatal intensive care admission. Premature babies can be up to 17...
Carolyn McGregor, Michael Stacey
RECOMB
2010
Springer
13 years 12 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
BMCBI
2008
84views more  BMCBI 2008»
13 years 10 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
TASLP
2010
137views more  TASLP 2010»
13 years 8 months ago
High-Pitch Formant Estimation by Exploiting Temporal Change of Pitch
—This paper considers the problem of obtaining an accurate spectral representation of speech formant structure when the voicing source exhibits a high fundamental frequency. Our ...
Tianyu T. Wang, Thomas F. Quatieri