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BMCBI
2011
14 years 10 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
BMCBI
2011
14 years 10 months ago
Tiling array data analysis: a multiscale approach using wavelets
Background: Tiling array data is hard to interpret due to noise. The wavelet transformation is a widely used technique in signal processing for elucidating the true signal from no...
Alexander Karpikov, Joel S. Rozowsky, Mark Gerstei...
BMCBI
2011
14 years 10 months ago
Appearance frequency modulated gene set enrichment testing
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
Jun Ma, Maureen A. Sartor, H. V. Jagadish
BMCBI
2011
14 years 10 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...
134
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CORR
2011
Springer
158views Education» more  CORR 2011»
14 years 10 months ago
SqFreeEVAL: An (almost) optimal real-root isolation algorithm
Let f be a univariate polynomial with real coefficients, f ∈ R[X]. Subdivision algorithms based on algebraic techniques (e.g., Sturm or Descartes methods) are widely used for is...
Michael Burr, Felix Krahmer