Abstract. Applied Biosystems’ SOLiD system offers a low-cost alternative to the traditional Sanger method of DNA sequencing. We introduce two main algorithms of mapping SOLiD’...
The tree representation of evolutionary relationship oversimplifies the view of the process of evolution as it cannot take into account the events such as horizontal gene transfer...
M. A. H. Zahid, Ankush Mittal, Ramesh Chandra Josh...
In the STS-based mapping, we are requested to obtain the correct order of probes in a DNA sequence from a given set of fragments or equivalently a hybridization matrix A. It is wel...
For the last twenty years fragment assembly in DNA sequencing followed the "overlap - layout - consensus" paradigm that is used in all currently available assembly tools...
: Despite many years of research on how to properly align sequences in the presence of sequencing errors, alternative splicing and micro-exons, the correct alignment of mRNA sequen...