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» Hybrid Genetic Algorithm for DNA Sequencing with Errors
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ICCS
2005
Springer
14 years 1 months ago
SWAT: A New Spliced Alignment Tool Tailored for Handling More Sequencing Errors
Abstract. There are several computer programs that align mRNA with its genomic counterpart to determine exon boundaries. Though most of these programs perform such alignment effici...
Yifeng Li, Hesham H. Ali
BIOCOMP
2010
13 years 4 months ago
Using the Genetic Code Wisdom for Recognizing Protein Coding Sequences
We have elaborated a new method of recognizing protein coding sequences in genomic sequences. The method is exploiting a specific way of genetic code degeneration and relations bet...
Pawel Blazej, Pawel Mackiewicz, Stanislaw Cebrat
BMCBI
2010
101views more  BMCBI 2010»
13 years 7 months ago
Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
Background: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variat...
Zhengdong D. Zhang, Mark B. Gerstein
IPPS
2003
IEEE
14 years 23 days ago
Accurate Method for Fast Design of Diagnostic Oligonucleotide Probe Sets for DNA Microarrays
We present a method for the automatic generation of oligonucleotide probe sets for DNA microarrays. This approach is well suited particularly for specificity evaluation of design...
Andreas Krause, Markus Kräutner, Harald Meier
WABI
2005
Springer
110views Bioinformatics» more  WABI 2005»
14 years 29 days ago
Alignment of Tandem Repeats with Excision, Duplication, Substitution and Indels (EDSI)
Abstract. Traditional sequence comparison by alignment applies a mutation model comprising two events, substitutions and indels (insertions or deletions) of single positions (SI). ...
Michael Sammeth, Thomas Weniger, Dag Harmsen, Jens...