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» Hybrid Genetic Algorithm for DNA Sequencing with Errors
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CEC
2007
IEEE
13 years 11 months ago
Efficient assembling of genome fragments using genetic algorithm enhanced by heuristic search
Abstract-- Shotgun sequencing is the state-of-the-art to decode genome sequence. However this technique needs a lot of fragments. Combining those fragments correctly requires enorm...
Satoko Kikuchi, Goutam Chakraborty
IPPS
2010
IEEE
13 years 5 months ago
pFANGS: Parallel high speed sequence mapping for Next Generation 454-roche Sequencing reads
Millions of DNA sequences (reads) are generated by Next Generation Sequencing machines everyday. There is a need for high performance algorithms to map these sequences to the refer...
Sanchit Misra, Ramanathan Narayanan, Wei-keng Liao...
GCB
2000
Springer
137views Biometrics» more  GCB 2000»
13 years 11 months ago
Detecting Sporadic Recombination in DNA Alignments with Hidden Markov Models
Conventional phylogenetic tree estimation methods assume that all sites in a DNA multiple alignment have the same evolutionary history. This assumption is violated in data sets fro...
Dirk Husmeier, Frank Wright
BIOINFORMATICS
2010
170views more  BIOINFORMATICS 2010»
13 years 7 months ago
Joint estimation of DNA copy number from multiple platforms
DNA copy number variants (CNV) are gains and losses of segments of chromosomes, and comprise an important class of genetic variation. Recently, various microarray hybridization ba...
Nancy R. Zhang, Yasin Senbabaoglu, Jun Z. Li
BMCBI
2006
115views more  BMCBI 2006»
13 years 7 months ago
Detecting recombination in evolving nucleotide sequences
Background: Genetic recombination can produce heterogeneous phylogenetic histories within a set of homologous genes. These recombination events can be obscured by subsequent resid...
Cheong Xin Chan, Robert G. Beiko, Mark A. Ragan