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CCE
2008
13 years 7 months ago
Informative gene selection and design of regulatory networks using integer optimization
A central problem in bioinformatics and systems biology is the selection of appropriate models in a rational and systematic way. This fundamentally combinatorial problem can be re...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Ioa...
FSTTCS
2009
Springer
14 years 2 months ago
Iterative Methods in Combinatorial Optimization
We describe a simple iterative method for proving a variety of results in combinatorial optimization. It is inspired by Jain’s iterative rounding method (FOCS 1998) for designing...
R. Ravi
HIS
2008
13 years 9 months ago
Towards a Highly Scalable Hybrid Metaheuristic for Haplotype Inference Under Parsimony
Haplotype Inference is a challenging problem in bioinformatics that consists in inferring the basic genetic constitution of diploid organisms on the basis of their genotype. This ...
Stefano Benedettini, Luca Di Gaspero, Andrea Roli
CEC
2010
IEEE
13 years 8 months ago
Local Optima Networks of the Quadratic Assignment Problem
Using a recently proposed model for combinatorial landscapes, Local Optima Networks (LON), we conduct a thorough analysis of two types of instances of the Quadratic Assignment Prob...
Fabio Daolio, Sébastien Vérel, Gabri...
ICIC
2007
Springer
14 years 1 months ago
A Hybrid Electromagnetism-Like Algorithm for Single Machine Scheduling Problem
Electromagnetism-like algorithm (EM) is a population-based meta-heuristic which has been proposed to solve continuous problems effectively. In this paper, we present a new meta-h...
Shih-Hsin Chen, Pei-Chann Chang, Chien-Lung Chan, ...