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» I-TASSER server for protein 3D structure prediction
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BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...
CONSTRAINTS
2008
182views more  CONSTRAINTS 2008»
13 years 7 months ago
Constraint Programming in Structural Bioinformatics
Bioinformatics aims at applying computer science methods to the wealth of data collected in a variety of experiments in life sciences (e.g. cell and molecular biology, biochemistry...
Pedro Barahona, Ludwig Krippahl
BMCBI
2005
92views more  BMCBI 2005»
13 years 7 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay
CIKM
2008
Springer
13 years 9 months ago
Intra-document structural frequency features for semi-supervised domain adaptation
In this work we try to bridge the gap often encountered by researchers who find themselves with few or no labeled examples from their desired target domain, yet still have access ...
Andrew Arnold, William W. Cohen
BMCBI
2008
176views more  BMCBI 2008»
13 years 7 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick