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BMCBI
2004
131views more  BMCBI 2004»
13 years 7 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
CSB
2004
IEEE
106views Bioinformatics» more  CSB 2004»
13 years 11 months ago
A Theoretical Analysis of Gene Selection
A great deal of recent research has focused on the challenging task of selecting differentially expressed genes from microarray data (`gene selection'). Numerous gene selecti...
Sach Mukherjee, Stephen J. Roberts
BMCBI
2008
107views more  BMCBI 2008»
13 years 8 months ago
A mixture model approach to sample size estimation in two-sample comparative microarray experiments
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
Tommy S. Jørstad, Herman Midelfart, Atle M....
BMCBI
2010
124views more  BMCBI 2010»
13 years 8 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2007
86views more  BMCBI 2007»
13 years 8 months ago
Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
William O. Ward, Carol D. Swartz, Steffen Porwolli...