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BMCBI
2008
142views more  BMCBI 2008»
13 years 8 months ago
Microarray data mining: A novel optimization-based approach to uncover biologically coherent structures
Background: DNA microarray technology allows for the measurement of genome-wide expression patterns. Within the resultant mass of data lies the problem of analyzing and presenting...
Meng Piao Tan, Erin N. Smith, James R. Broach, Chr...
BMCBI
2006
155views more  BMCBI 2006»
13 years 8 months ago
Analysis of promoter regions of co-expressed genes identified by microarray analysis
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
Srinivas Veerla, Mattias Höglund
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
Eva Freyhult, Mattias Landfors, Jenny Önskog,...
BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
13 years 8 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
GECCO
2005
Springer
156views Optimization» more  GECCO 2005»
14 years 1 months ago
Extraction of informative genes from microarray data
Identification of those genes that might anticipate the clinical behavior of different types of cancers is challenging due to availability of a smaller number of patient samples...
Topon Kumar Paul, Hitoshi Iba