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NAR
2002
141views more  NAR 2002»
13 years 7 months ago
Co-expression pattern from DNA microarray experiments as a tool for operon prediction
The prediction of operons, the smallest unit of transcription in prokaryotes, is the first step towards reconstruction of a regulatory network at the whole genome level. Sequence ...
Chiara Sabatti, Lars Rohlin, Min-Kyu Oh, James C. ...
BMCBI
2006
131views more  BMCBI 2006»
13 years 8 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
BMCBI
2004
169views more  BMCBI 2004»
13 years 8 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
IDA
2003
Springer
14 years 1 months ago
An Iterated Local Search Approach for Minimum Sum-of-Squares Clustering
Abstract. Since minimum sum-of-squares clustering (MSSC) is an NPhard combinatorial optimization problem, applying techniques from global optimization appears to be promising for r...
Peter Merz
BIOINFORMATICS
2007
190views more  BIOINFORMATICS 2007»
13 years 8 months ago
Towards clustering of incomplete microarray data without the use of imputation
Motivation: Clustering technique is used to find groups of genes that show similar expression patterns under multiple experimental conditions. Nonetheless, the results obtained by...
Dae-Won Kim, Ki Young Lee, Kwang H. Lee, Doheon Le...