A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...
Background: Genome-wide expression studies have developed exponentially in recent years as a result of extensive use of microarray technology. However, expression signals are typi...
A major challenge in microarray classification and biomarker discovery is dealing with small-sample high-dimensional data where the number of genes used as features is typically o...
Abstract. This paper introduces a novel method for processing spotted microarray images, inspired from image reconstruction. Instead of the usual approach that focuses on the signa...
Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...