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BMCBI
2010
167views more  BMCBI 2010»
13 years 8 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2006
86views more  BMCBI 2006»
13 years 8 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
BMCBI
2005
110views more  BMCBI 2005»
13 years 8 months ago
Considerations when using the significance analysis of microarrays (SAM) algorithm
Background: Users of microarray technology typically strive to use universally acceptable data analysis strategies to determine significant expression changes in their experiments...
Ola Larsson, Claes Wahlestedt, James A. Timmons