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    BMCBI
    2006
    112views more  BMCBI 2006»
    Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
    13 years 8 months ago
    Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
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    Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
    Lesley Jones, Darlene R. Goldstein, Gareth P. Hugh...
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    BMCBI
    2006
    87views more  BMCBI 2006»
    Computational expression deconvolution in a complex mammalian organ
    13 years 8 months ago
    Computational expression deconvolution in a complex mammalian organ
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    Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
    Min Wang, Stephen R. Master, Lewis A. Chodosh
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    BMCBI
    2006
    103views more  BMCBI 2006»
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
    13 years 8 months ago
    Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
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    Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
    Sébastien Lemieux
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    BMCBI
    2008
    113views more  BMCBI 2008»
    A novel application of quantile regression for identification of biomarkers exemplified by equine cartilage microarray data
    13 years 8 months ago
    A novel application of quantile regression for identification of biomarkers exemplified by equine cartilage microarray data
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    Background: Identification of biomarkers among thousands of genes arrayed for disease classification has been the subject of considerable research in recent years. These studies h...
    Liping Huang, Wenying Zhu, Christopher P. Saunders...
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    BMCBI
    2008
    126views more  BMCBI 2008»
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
    13 years 8 months ago
    c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
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    Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
    Katerina Kechris, Hao Li
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