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BMCBI
2005
121views more  BMCBI 2005»
13 years 8 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
BMCBI
2010
108views more  BMCBI 2010»
13 years 8 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...
BIBE
2007
IEEE
191views Bioinformatics» more  BIBE 2007»
14 years 2 months ago
PANP - a New Method of Gene Detection on Oligonucleotide Expression Arrays
Abstract. Currently, the method most used for gene detection calls on Affymetrix oligonucleotide arrays is provided as part of the MAS5.0 software. The MAS method uses Wilcoxon sta...
Peter Warren, Deanne Taylor, Paolo G. V. Martini, ...
BMCBI
2010
120views more  BMCBI 2010»
13 years 8 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...
BMCBI
2011
13 years 3 months ago
Appearance frequency modulated gene set enrichment testing
Background: Gene set enrichment testing has helped bridge the gap from an individual gene to a systems biology interpretation of microarray data. Although gene sets are defined a ...
Jun Ma, Maureen A. Sartor, H. V. Jagadish