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BMCBI
2007
168views more  BMCBI 2007»
13 years 8 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2007
123views more  BMCBI 2007»
13 years 8 months ago
Heritable clustering and pathway discovery in breast cancer integrating epigenetic and phenotypic data
Background: In order to recapitulate tumor progression pathways using epigenetic data, we developed novel clustering and pathway reconstruction algorithms, collectively referred t...
Zailong Wang, Pearlly Yan, Dustin P. Potter, Chari...
BMCBI
2007
116views more  BMCBI 2007»
13 years 8 months ago
Ranked Adjusted Rand: integrating distance and partition information in a measure of clustering agreement
Background: Biological information is commonly used to cluster or classify entities of interest such as genes, conditions, species or samples. However, different sources of data c...
Francisco R. Pinto, João A. Carriço,...
HIS
2008
13 years 9 months ago
CBR System for Diagnosis of Patients
Microarray technology allows to measure the expression levels of thousands of genes in an experiment. The use of computational methods is fundamental in cancer research. One of th...
Juan Francisco de Paz, Sara Rodríguez, Javi...
BMCBI
2007
176views more  BMCBI 2007»
13 years 8 months ago
Correlation-maximizing surrogate gene space for visual mining of gene expression patterns in developing barley endosperm tissue
Background: Micro- and macroarray technologies help acquire thousands of gene expression patterns covering important biological processes during plant ontogeny. Particularly, fait...
Marc Strickert, Nese Sreenivasulu, Björn Usad...